Shaping the Future of Regenerative Medicine

Pluripotent stem cell (PSC) therapies provide hope to patients with incurable diseases. But current cell therapy development and manufacturing approaches are fraught with difficulties.
We're here to change that.

We’re on a bold mission to cure the incurable.

Two promising cell therapies in the pipeline

We have two promising allogeneic stem cell therapies in the pipeline, with preclinical proof of concept data showing they can treat the disease in relevant large animal models.

ALD01 - Hope for those with Retinitis Pigmentosa

Our first and most advanced program is a retinal cell therapy to treat Retinitis Pigmentosa (RP), a debilitating inherited blindness disease affecting 1 in 4,000 people worldwide. Eventually it could be used to treat any cone or rod-based retinal diseases.

Current treatments for RP are limited to one single-mutation gene therapy with few eligible patients. For the others, there are no treatment options.

ALD01 could revolutionize RP treatment, offering a mutation agnostic option for almost all patients.

What’s more, ALD01 is supported by highly promising preclinical data and boasts numerous advantages over other RP cell therapies in development.

ALD02 - Tackling heart failure

Heart failure (HF) is the most common cause of death worldwide. But current treatment options are often invasive and/or expensive, or just treat the symptoms.

ALD02 will be our second program, a cardiac cell therapy that has also shown promising preclinical data and aims to restore heart function.

More about Our Therapies

Two promising cell therapies in the pipeline

We have two promising allogeneic stem cell therapies in the pipeline, with pre-clinical proof of concept data showing they can treat the disease in relevant large animal models.

ALD01: Hope for those with Retinitis Pigmentosa

ALD01 is a retinal cell therapy to treat Retinitis Pigmentosa (RP), a debilitating inherited blindness disease affecting 1 in 4,000 people worldwide.1 Eventually it could be used to treat any cone or rod-based retinal diseases.

Current treatments for RP are limited to one single-mutation gene therapy with few eligible patients. For the others, there are no treatment options.

ALD01 could revolutionize RP treatment, offering a mutation agnostic option for almost all patients.

What’s more, ALD01 is supported by highly promising preclinical data and boasts numerous advantages over other RP cell therapies in development.

ALD02: Tackling heart failure

Heart failure (HF) is the most common cause of death worldwide. But current treatment options are often invasive and/or expensive, or just treat the symptoms.

ALD02 is a cardiac cell therapy that aims to change this by restoring the heart function.

ALD02 is also supported by promising, high-quality pre-clinical data, and offers numerous advantages over other cell therapies for HF.

1.       O'Neal TB, Luther EE. Retinitis Pigmentosa. [Updated2023 Feb 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearlsPublishing; 2023 Jan-.

More about Our Therapies

The AlderEdge approach

Reimagining cell therapy development

Traditional approaches to bringing cell therapies to market are fraught with challenges — from high-risk development and unpredictable manufacturing processes to unreliable income models. So, we developed the AlderEdge, a unique drug development philosophy that de-risks the development of cell therapies. By keeping the commercial product in mind from the start, the AlderEdge approach de-risks development, helping to bring advanced cell therapies to market, faster, and more reliably.

Discover more about the AlderEdge approach.

Get in touch

Interested in shaping the evolution of regenerative medicine? Get in touch to find out more.

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